Order ID:89JHGSJE83839 | Style:APA/MLA/Harvard/Chicago | Pages:5-10 |
Instructions:
Alzheimer Disease and Abeta Peptides Summary
I want a summary of Alzheimer Disease that answer all or most of these:
1)Structure and pI of Abeta
2)How Abeta peptides are generated in the brain
3)Chronologic relation between Abeta 42 and 40 generation and the progression of Alzheimer’s disease pathology, vascular dementia, and Down syndrome.
4)The different morphology of mature plaque vs primitive plaque with different Abeta 42 and 40
5)Are bundles present in plaques with Abeta42, Abeta 40 or a mixture of the two kinds of peptides
6)Abeta 42 and 40 amyloid fiber formation pathways
7)Abeta 42 and 40 oligomers size, diameter and number of monomers
8)Abeta 42 and 40 mixture at different ratio and the effect on fiber formation
9)Speculate how abeta 40 may affect Abeta 42 aggregation and formation of oligomers and fibers
10)Speculate how extracelluar matrix such as charged polymers and noncharged polymers affect fiber formation.
11)Guess or Speculate how metal (Copper, Zinc, Calcium) ions such as those found in the plaque affect the fiber formation
12)Speculate how lipid molecules affect fiber formation
RUBRIC |
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Excellent Quality 95-100%
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Introduction
45-41 points The background and significance of the problem and a clear statement of the research purpose is provided. The search history is mentioned. |
Literature Support 91-84 points The background and significance of the problem and a clear statement of the research purpose is provided. The search history is mentioned. |
Methodology 58-53 points Content is well-organized with headings for each slide and bulleted lists to group related material as needed. Use of font, color, graphics, effects, etc. to enhance readability and presentation content is excellent. Length requirements of 10 slides/pages or less is met. |
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Average Score 50-85% |
40-38 points More depth/detail for the background and significance is needed, or the research detail is not clear. No search history information is provided. |
83-76 points Review of relevant theoretical literature is evident, but there is little integration of studies into concepts related to problem. Review is partially focused and organized. Supporting and opposing research are included. Summary of information presented is included. Conclusion may not contain a biblical integration. |
52-49 points Content is somewhat organized, but no structure is apparent. The use of font, color, graphics, effects, etc. is occasionally detracting to the presentation content. Length requirements may not be met. |
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Poor Quality 0-45% |
37-1 points The background and/or significance are missing. No search history information is provided. |
75-1 points Review of relevant theoretical literature is evident, but there is no integration of studies into concepts related to problem. Review is partially focused and organized. Supporting and opposing research are not included in the summary of information presented. Conclusion does not contain a biblical integration. |
48-1 points There is no clear or logical organizational structure. No logical sequence is apparent. The use of font, color, graphics, effects etc. is often detracting to the presentation content. Length requirements may not be met |
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Alzheimer Disease and Abeta Peptides Summary |
Alzheimer Disease and Abeta Peptides Summary