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Biology Immunology Multiple Choice Term Paper Questions
In order to diagnose Mycobacterium tuberculosis (MTB) infection, doctors commonly perform the Mantoux. it involves injecting tuberculin antigens (a glycerol extract of MTB) under the skin and waiting for 24 – 48h for the development of a swollen red lump at the injection site. The presence of a positive reaction after 24h in an MTB-infected patient would be due to which of the following:
Select one:
a.
Re-activation of existing MTB-specific TH1 responses at the site of injection
b.
Triggering of mast cell degranulation due to binding of MTB-specific IgE at the site of injection
c.
Re-activation of existing MTB-specific CD8 T cell responses at the site of injection
d.
Recruitment of neutrophils after release of IL-8 from resting macrophages
e.
Complement-mediated lysis of macrophages binding to tuberculin at the site of injection
Lymphocyte anergy to self-antigens is defined as?
Select one:
a.
Elimination of self-reactive lymphocytes from the body before activation
b.
Apoptosis of self-reactive lymphocytes after activation
c.
Activation of self-reactive lymphocytes aftre antigen encounter
d.
Inactivation of self-reactive lymphocytes after antigen encounter
Central tolerance of T cells towards self-antigens develops where?
Select one:
a.
In the thymus in early life
b.
In the thymus after infection
c.
In the spleen and lymph nodes
d.
In the gut in early life
e.
After peripheral tolerance has failed
IgM is a key defence molecule found in serum and crosses the placenta in the last trimester of pregnancy to provide the newborn human with passive immunity from its mother.
Select one:
a.True
b.False
c.Only in some pregnancies
Rejection of a xenograft (a graft from a different species) would most likely be caused by which of the following?
Select one:
a.CD4 and CD8 effector T cell responses that develop within weeks
b.Pre-existing, cross-reactive antibodies against the graft
c.Development of anti-graft antibodies over time
d.Memory CD8 responses present from previous grafts
e.NK cell responses against graft MHC molecules
Glycoconjugate vaccines (where polysaccharide antigens from a pathogen are chemically linked to a protein antigen) are a major breakthrough in infant/childhood vaccination because they?
Select one:
a.Allow better anti-protein responses to encapsulated bacteria
b.
Enable strong and lasting IgM responses to be induced
c.
Covert T-independent responses into T-dependent responses
d.
Engage cytotoxic T cells as well as antibody production
e.
Allow children to make IgE responses to polysaccharide antigens
You are asked to help diagnose a patient presenting with severe, recurrent Staphylococcus aureus infections of the synovial fluid around the knees. When considering possible immunological explanations for this patient’s condition, which of the following conditions should you consider first?
Select one:
a.
Primary deficiencies of phagocyte function
b.
Primary deficiencies of NK function
c.
Primary deficiencies of antibody function
d.
Primary deficiencies of lymphocyte function
e.
An acquired immune deficiency
Allograft transplantation occurs when a donor receives an organ/graft from?
Select one:
a.
An identical twin
b.
Some other site on their body
c.
A different donor of the same species
d.
A different donor of a different species
Biology Immunology Multiple Choice Term Paper Questions
RUBRIC |
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Excellent Quality 95-100%
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Introduction
45-41 points The background and significance of the problem and a clear statement of the research purpose is provided. The search history is mentioned. |
Literature Support 91-84 points The background and significance of the problem and a clear statement of the research purpose is provided. The search history is mentioned. |
Methodology 58-53 points Content is well-organized with headings for each slide and bulleted lists to group related material as needed. Use of font, color, graphics, effects, etc. to enhance readability and presentation content is excellent. Length requirements of 10 slides/pages or less is met. |
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Average Score 50-85% |
40-38 points More depth/detail for the background and significance is needed, or the research detail is not clear. No search history information is provided. |
83-76 points Review of relevant theoretical literature is evident, but there is little integration of studies into concepts related to problem. Review is partially focused and organized. Supporting and opposing research are included. Summary of information presented is included. Conclusion may not contain a biblical integration. |
52-49 points Content is somewhat organized, but no structure is apparent. The use of font, color, graphics, effects, etc. is occasionally detracting to the presentation content. Length requirements may not be met. |
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Poor Quality 0-45% |
37-1 points The background and/or significance are missing. No search history information is provided. |
75-1 points Review of relevant theoretical literature is evident, but there is no integration of studies into concepts related to problem. Review is partially focused and organized. Supporting and opposing research are not included in the summary of information presented. Conclusion does not contain a biblical integration. |
48-1 points There is no clear or logical organizational structure. No logical sequence is apparent. The use of font, color, graphics, effects etc. is often detracting to the presentation content. Length requirements may not be met |
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Biology Immunology Multiple Choice Term Paper Questions |
Biology Immunology Multiple Choice Term Paper Questions