Case study on the mechanism of action of digoxin
Order ID: 89JHGSJE83839 Style: APA/MLA/Harvard/Chicago Pages: 5-10 Instructions:
1. Look up the word “decompensated heart failure” in the dictionary. What are the most common clinical symptoms and signs?
2. Could you recommend a medicine and its mode of action for reducing Mr Genadaire’s peripheral oedema?
With the modifications in his medication, Mr Genadaire’s peripheral oedema was resolved (weight dropped from 85.7kg on initial visit to 72.6kg) on his final visit to the clinic two months later.
He claimed to be in good health, and all of his other parameters were within normal limits, except for his renal function, which had deteriorated, with creatinine levels rising to 244 micromol/L (normal 60110)
and urea levels rising to 35.7 mg/dL (normal 620). The levels of sodium and potassium were both within normal limits. His renal function had abruptly decreased, which was perplexing. Further interrogation
revealed that he had recently returned from Africa and had been suffering from acute diarrhoea and vomiting, which had since stopped. Bumetanide 1 mg twice a day, spironolactone 25 mg once a day, aspirin
75 mg once a day, metformin 1 mg twice a day, NovoMix® 30 (biphasic insulin aspart), ramipril 5 mg twice a day, simvastatin 40 mg once a day, bisoprolol 3.75 mg once a day, and bendroflumethiazide 5 mg
twice weekly were
5. Which of Mr. Genadaire’s medications would you temporarily stop giving him in order to improve his renal function?
6. Could you recommend a test that would provide a more accurate assessment of Mr Genadaire’s renal function?
RUBRIC
Excellent Quality
95-100%
Introduction 45-41 points
The background and significance of the problem and a clear statement of the research purpose is provided. The search history is mentioned.
Literature Support
91-84 points
The background and significance of the problem and a clear statement of the research purpose is provided. The search history is mentioned.
Methodology
58-53 points
Content is well-organized with headings for each slide and bulleted lists to group related material as needed. Use of font, color, graphics, effects, etc. to enhance readability and presentation content is excellent. Length requirements of 10 slides/pages or less is met.
Average Score
50-85%
40-38 points
More depth/detail for the background and significance is needed, or the research detail is not clear. No search history information is provided.
83-76 points
Review of relevant theoretical literature is evident, but there is little integration of studies into concepts related to problem. Review is partially focused and organized. Supporting and opposing research are included. Summary of information presented is included. Conclusion may not contain a biblical integration.
52-49 points
Content is somewhat organized, but no structure is apparent. The use of font, color, graphics, effects, etc. is occasionally detracting to the presentation content. Length requirements may not be met.
Poor Quality
0-45%
37-1 points
The background and/or significance are missing. No search history information is provided.
75-1 points
Review of relevant theoretical literature is evident, but there is no integration of studies into concepts related to problem. Review is partially focused and organized. Supporting and opposing research are not included in the summary of information presented. Conclusion does not contain a biblical integration.
48-1 points
There is no clear or logical organizational structure. No logical sequence is apparent. The use of font, color, graphics, effects etc. is often detracting to the presentation content. Length requirements may not be met
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