How Mutations Can Uncouple Chromosomal Sex from Phenotypic Sex
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How Mutations Can Uncouple Chromosomal Sex from Phenotypic Sex
- Give an example of a situation in which genetic sex, gonadal sex, and phenotypic sex do not coincide. Explain why they do not coincide.
- How can an individual who is XY be phenotypically female?
- Discuss whether the following individuals (1) have male or female gonads, (2) are phenotypically male or female (discuss Wolffi an/Müllerian ducts and external genitalia), and (3) are sterile or fertile.
- XY, homozygous for a recessive mutation in the testosterone biosynthetic pathway, producing no testosterone
- XX, heterozygous for a dominant mutation in the testosterone biosynthetic pathway, which causes continuous production of testosterone
- XY, heterozygous for a recessive mutation in the MIH gene
- XY, homozygous for a recessive mutation in the SRY gene that abolishes function
RUBRIC
Excellent Quality
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Introduction 45-41 points
The background and significance of the problem and a clear statement of the research purpose is provided. The search history is mentioned.
Literature Support
91-84 points
The background and significance of the problem and a clear statement of the research purpose is provided. The search history is mentioned.
Methodology
58-53 points
Content is well-organized with headings for each slide and bulleted lists to group related material as needed. Use of font, color, graphics, effects, etc. to enhance readability and presentation content is excellent. Length requirements of 10 slides/pages or less is met.
Average Score
50-85%
40-38 points
More depth/detail for the background and significance is needed, or the research detail is not clear. No search history information is provided.
83-76 points
Review of relevant theoretical literature is evident, but there is little integration of studies into concepts related to problem. Review is partially focused and organized. Supporting and opposing research are included. Summary of information presented is included. Conclusion may not contain a biblical integration.
52-49 points
Content is somewhat organized, but no structure is apparent. The use of font, color, graphics, effects, etc. is occasionally detracting to the presentation content. Length requirements may not be met.
Poor Quality
0-45%
37-1 points
The background and/or significance are missing. No search history information is provided.
75-1 points
Review of relevant theoretical literature is evident, but there is no integration of studies into concepts related to problem. Review is partially focused and organized. Supporting and opposing research are not included in the summary of information presented. Conclusion does not contain a biblical integration.
48-1 points
There is no clear or logical organizational structure. No logical sequence is apparent. The use of font, color, graphics, effects etc. is often detracting to the presentation content. Length requirements may not be met
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How Mutations Can Uncouple Chromosomal Sex from Phenotypic Sex