Order ID:89JHGSJE83839 | Style:APA/MLA/Harvard/Chicago | Pages:5-10 |
Instructions:
Properties to Prioritize in An Optimization Program Questions
Part 1.
Choose three properties that you would prioritize if you were running a lead optimization program and explain the primary reasons for you choices. ( 1 paragraph 10-11 sentences)
Read the referenced article and provide your comments as the contents applies to clinical trial design.http://ascopubs.org/doi/full/10.1200/jco.2010.31.7024 ( 1 paragraph 10-11 sentences)
Part 2
1.) Using the referenced file, if putting together a clinical research study budget is nothing more involved than creating a MS Excel spreadsheet, why do we find researchers, authors, and even consultants dedicated to the subject?- 1 page
2.) What are the differences between descriptive, comparative, and inferential statistics?
sorry for the delay I know have question 3: In 2005, 72,007 men and 69,398 women were diagnosed with colorectal cancer. Assume that you are the statistician designing a clinical trial for a new drug that purports to cure this disease. Using the referenced website, what would your recommended sample size be, given a 5% margin of error and a 95% confidence level? http://www.raosoft.com/samplesize.htmlThe DeGoey et al., paper describes numerous clinically effective drugs that have one or more properties “beyond” Lipinski’s Rule of 5. Is it time to replace Lipinski’s rules with a more current set of rules based on recent experience? If so, what parameters would these new rules include? Would they be applied to every program? Would they be applied at the very beginning of the program? 7-9 SENTENCES
In 2005, 72,007 men and 69,398 women were diagnosed with colorectal cancer. Assume that you are the statistician designing a clinical trial for a new drug that purports to cure this disease. Using the referenced website, what would your recommended sample size be, given a 5% margin of error and a 95% confidence level? http://www.raosoft.com/samplesize.html
RUBRIC |
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Excellent Quality 95-100%
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Introduction
45-41 points The background and significance of the problem and a clear statement of the research purpose is provided. The search history is mentioned. |
Literature Support 91-84 points The background and significance of the problem and a clear statement of the research purpose is provided. The search history is mentioned. |
Methodology 58-53 points Content is well-organized with headings for each slide and bulleted lists to group related material as needed. Use of font, color, graphics, effects, etc. to enhance readability and presentation content is excellent. Length requirements of 10 slides/pages or less is met. |
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Average Score 50-85% |
40-38 points More depth/detail for the background and significance is needed, or the research detail is not clear. No search history information is provided. |
83-76 points Review of relevant theoretical literature is evident, but there is little integration of studies into concepts related to problem. Review is partially focused and organized. Supporting and opposing research are included. Summary of information presented is included. Conclusion may not contain a biblical integration. |
52-49 points Content is somewhat organized, but no structure is apparent. The use of font, color, graphics, effects, etc. is occasionally detracting to the presentation content. Length requirements may not be met. |
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Poor Quality 0-45% |
37-1 points The background and/or significance are missing. No search history information is provided. |
75-1 points Review of relevant theoretical literature is evident, but there is no integration of studies into concepts related to problem. Review is partially focused and organized. Supporting and opposing research are not included in the summary of information presented. Conclusion does not contain a biblical integration. |
48-1 points There is no clear or logical organizational structure. No logical sequence is apparent. The use of font, color, graphics, effects etc. is often detracting to the presentation content. Length requirements may not be met |
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Properties to Prioritize in An Optimization Program Questions |
Properties to Prioritize in An Optimization Program Questions