Clinical Genetic Settings and Biological Entities Questions
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Clinical Genetic Settings and Biological Entities Questions
Inevitability of Cancer Discussion
Genetic mutation is what leads to the mechanism of natural selection, and thus contributes directly to evolution, a necessary and useful process. The crossing over and randomization at fertilization also increases variation. Without the variation that results from mutations, natural selection would not occur, thus proving that genetic mutations are beneficial and crucial for life. However, cancer is a disease caused by mutation. Does this mean that cancer is inescapable for all humans if we simply live long enough?
Clinical Genetic Settings and Biological Entities Questions
Discuss how the primary structure of nucleic acids is the order of bases in the polynucleotide sequence, and the secondary structure is the three-dimensional conformation of the backbone.
Discuss the monomers of nucleic acids are nucleotides.
Discuss how the bases are bonded to the sugars, forming nucleosides.
Summarize how nucleosides are linked by ester bonds to phosphoric acid to form the phosphodiester backbone.
Specific proteins called single-strand binding proteins bind to the single-stranded regions and protect them from nucleases.
Spontaneous mutation of bases and insertion of the wrong nucleotide would normally lead to an error every 104 to 105
Instructions:
Step 1: Read the article found in section 9A: Biochemical Connections: Law in your digital book.
Using the Concorde’s Online Library, your digital material, and other scholarly websites, discuss the following:
What are your feelings regarding the article?
Describe, in detail, what the following statement means, “What can be patented is purified DNA containing the sequence of the gene and techniques that allow the study of the genes.”
How do you see the patenting of genes/DNA impacting science and medicine over the next 30 years?
Do you believe this trend is ethical? Why/why not?
Clinical Genetic Settings and Biological Entities Questions
Clinical Genetic Settings and Biological Entities Questions
RUBRIC
Excellent Quality
95-100%
Introduction 45-41 points
The background and significance of the problem and a clear statement of the research purpose is provided. The search history is mentioned.
Literature Support
91-84 points
The background and significance of the problem and a clear statement of the research purpose is provided. The search history is mentioned.
Methodology
58-53 points
Content is well-organized with headings for each slide and bulleted lists to group related material as needed. Use of font, color, graphics, effects, etc. to enhance readability and presentation content is excellent. Length requirements of 10 slides/pages or less is met.
Average Score
50-85%
40-38 points
More depth/detail for the background and significance is needed, or the research detail is not clear. No search history information is provided.
83-76 points
Review of relevant theoretical literature is evident, but there is little integration of studies into concepts related to problem. Review is partially focused and organized. Supporting and opposing research are included. Summary of information presented is included. Conclusion may not contain a biblical integration.
52-49 points
Content is somewhat organized, but no structure is apparent. The use of font, color, graphics, effects, etc. is occasionally detracting to the presentation content. Length requirements may not be met.
Poor Quality
0-45%
37-1 points
The background and/or significance are missing. No search history information is provided.
75-1 points
Review of relevant theoretical literature is evident, but there is no integration of studies into concepts related to problem. Review is partially focused and organized. Supporting and opposing research are not included in the summary of information presented. Conclusion does not contain a biblical integration.
48-1 points
There is no clear or logical organizational structure. No logical sequence is apparent. The use of font, color, graphics, effects etc. is often detracting to the presentation content. Length requirements may not be met
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